Abstract Polyketide synthases (PKSs) are crucial multidomain enzymes in diverse natural product biosynthesis.Parrots use a type I PKS to produce a unique pigment called psittacofulvin in their feathers.In domesticated budgerigars and lovebirds, the same amino acid substitution (R644W) within malonyl/acetyltransferase (MAT) domain of this enzyme has
Abstract Background Mild acute biliary pancreatitis (MABP) presents significant clinical and economic challenges due to its potential for relapse.Current guidelines advocate for early cholecystectomy (EC) during the same hospital admission to prevent recurrent acute pancreatitis (RAP).Despite these recommendations, implementation in clinical practi
Conditional punishment is a Shirts men’s Cinch red geometric print button up form of punishment that does not result in the deprivation of the rights from convicted person.In the juvenile justice system are different from adults.The purpose of this research is to know and understand the parole (conditional punishment) comparison of the Criminal C
Based on previous large-scale in silico screening several factor Xa inhibitors were proposed to potentially inhibit SARS-CoV-2 5.3 Mpro.In addition to their known anticoagulants activity this potential inhibition could have an additional therapeutic effect on patients with COVID-19 disease.In this study we examined the binding of the Apixaban, Betr